Wegovy (semaglutide) and phentermine operate through distinct biological pathways, and combining them carries specific cardiovascular and metabolic risks that require careful medical evaluation
Nov 19 2018;16(1):108
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More recent results from the STEP UP trial show that higher doses can lead to an average weight loss of about 21%, with some individuals losing 25% or more of their starting weight, offering even greater potential for improved health and confidence
[DOI] [PubMed] [Google Scholar] 57.Wilson DM, Liedtke RR
When initiating semaglutide in patients already taking insulin or sulfonylureas, consider reducing the doses of these medications to mitigate the risk of hypoglycemia