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Animal studies have shown that GLP-1 receptors are present on bone cells, including osteoblasts and osteoclasts, suggesting a potential direct effect on bone metabolism, though the clinical relevance in humans remains uncertain

We also discuss the possible causes and when to see a doctor

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A 2023 systematic review with meta-analysis showed that GLP-1 agonists significantly reduced body weight (11.7lb mean difference), body mass index (2.4kg/m2) and waist circumference (1.7 inches) in non-diabetic obese or overweight patients

Can microdosing GLP-1s impact mood or psychiatric stability