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The study concluded that long-term antioxidant therapy with NAC helped prevent the development of pre-diabetes, dyslipidemia, and liver inflammation in obese rats, largely by reducing oxidative stress
As expected, hepsin / mice displayed heightened oxidative stress after APAP exposure compared to wild-type mice, indicated by a significant decrease in GSH and an increase in nitrotyrosine levels, leading to more severe liver damage and mortality
Vanin-1 activity is thought to counteract PPAR, as evidenced by the anti-inflammatory phenotypes of vanin-1-deficient mice that PPAR inhibitors inhibited (124)
Data presented are representative of three independent experiments
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a randomised clinical trial
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