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It may cause liver injury by inhibition of cyclooxygenase or cytochrome P450 activity or through an immune-mediated response

The mechanisms and results differ accordingly

Though it is fully funded with special authority approval, supply issues mean it has become inaccessible to many despite increased demand

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Physical activity increases blood flow to muscles and surrounding tissue, which can accelerate medication absorption beyond the intended rate

For the 144 FEHB plans available in 2024 and 2025, self only premiums will decrease in 28 plans, stay the same in 5 plans, increase below the 13.5% average in 69 plans, and increase above the average in 42 plans