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If no additional deformity was observed during two subsequent minutes or if additional recovery was achieved, these points were estimated as final (in general, the time of measuring was approximately 30 seconds (ovariectomized control) or 16 minutes (healthy))

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[DOI] [PubMed] [Google Scholar] 10.Obadia N, Andrade G, Leardini-Tristo M, Albuquerque L, Garcia C, Lima F, et al

it is those nevi with increasingly marked pigmentation, or appearing de novo in the older age groups, which are often excised for histological evaluation