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This creates a situation in which patients with certain comorbidities have access, while others with similar weight-related risks do not

Orforgliprons approval highlights both the growing role of GLP-1 therapies in weight loss and the potential for faster regulatory pathways, bringing new treatments to patients sooner

A brain-only approach can miss important modifiable risks elsewhere in the body

Tirzepatide has an elimination half-life of approximately 5 days (approximately 120 hours), which is a critical pharmacokinetic parameter that enables once-weekly dosing