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[DOI] [PMC free article] [PubMed] [Google Scholar] Millikin R, Bianco CL, White C, Saund SS, Henriquez S, Sosa V, Akaike T, Kumagai Y, Soeda S, Toscano JP, et al

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Down-regulation of the K + Cl co-transporter KCC2 has been reported in multiple studies 3,4,5,6,7

In most healthy cells, this ratio is maintained in a highly reduced state between 30:1 and 100:1