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Protective effects of diallyl disulfide on carbon tetrachloride-induced hepatotoxicity through activation of Nrf2

BtaGSTA1-1, an alpha class GST identified in tight association with bovine steroidogenically active cells and shown to be hormonally regulated by gonadotropins in the bovine ovarian follicles, appeared to be a likely isomerase ( Based on mutational studies of human GSTs the five H-site residues in positions 10, 12, 111, 208, and 216 were judged to be of particular importance for the ketosteroid isomerase activity (Table 1)

Glutathione protects mitochondria from oxidative damage, ensuring they function efficiently

Medicine 97(37):e12172

The role of albumin and alpha-1 antitrypsin in antioxidant defense is also discussed

Alin P, Danielson UH, Mannervik B