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Brain food intake & body weight Liver gluconeogenesis & steatosis Muscle glucose uptake & metabolic flexibility Adipose inflammation, insulin sensitivity Preclinical results (mouse model) vs GLP-1/GIP alone: Greater body weight reduction Stronger blood glucose lowering Better insulin sensitivity Less hepatic glucose production BUT not ready for clinic: Early preclinical stage only Human safety unknown PPAR agonism has mixed CV/renal history If it translates to humans, this could redefine metabolic disease treatment beyond anything we have today

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Thats actually a very unhealthy way to live. People who live in blue zones tend to live a life than allows them to move all day long Theyre working outside in the sunshine constantly, walking long distances, carrying/lifting things So what can you do

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( B ) Histogram showing the number and percentage of renal rhythmic transcripts assigned to dryR rhythmicity models

Mejoran la digestin