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The following considerations can be underlined, taking into account this controversy and the results obtained from this review: (i) According to the results analyzed here, NAC is preferentially used instead of l-Cys

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Removing it disrupts this interaction and reduces binding protein affinity, similar in principle to IGF-1 LR3 but through a different structural mechanism

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Another study also indicated that exendin-4 improved memory impairment by dampening the AMPK/NF-B pathway, reducing levels of IL-1 and TNF-, and increasing synaptic protein levels (40)