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As a result the structure observed is often dependent on ligand-based constraints, crystal packing, and solvent effects that preference one geometry over the others
Research published in Neuropsychopharmacology confirmed this pathway, demonstrating that the sleep-promoting effects of glycine are mediated specifically through these receptors
The study was published in Proceedings of the National Academy of Sciences on March 4, 2026, and was funded by federal research grants from the National Institutes of Health and private philanthropy
doi: 10.1111/dom.13129 31
