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Treatment discontinuation (46%) was the most common reason for censoring (Supplementary Table 20)

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In contrast, certain studies have indicated no significant alterations in plasma ghrelin levels during fasting [54]

In the AWARD-7 trial (which was not a CVOT) performed in T2DM subjects with moderate-to-severe CKD, onceweekly dulaglutide produced glycemic control similar to that achieved with insulin glargine, but showed evidence of reduced decline in eGFR (64)