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There appears to be species differences in cell maturation after transplantation, with mouse precursors differentiating into mature astrocytes more robustly than human precursors ([37, 83]

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52 Concurrently, AMPK inhibits hepatic gluconeogenesis, an effect in large part responsible for the favourable impact of AMPK agonists on glycaemic control in diabetics

2012 displays favorable DMPK properties and in vivo efficacy To ensure suitability for in vivo testing, a series of in vitro DMPK assays were performed to assess plasma and metabolic stability of 2012

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