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High doses of B12, often used to treat deficiencies, may cause side effects such as headaches, nausea, diarrhea, fatigue or weakness, and tingling in the hands and feet

Guarana (Paullinia cupana)

Poor hydration, reduced renal function or low buffering capacity may make SAH accumulation more difficult to correct

Even subcutaneous doses of endotoxin-contaminated product can provoke local and systemic inflammatory cascades

But it is not what you reach for when a patients primary complaint is systemic fatigue or cognitive fog

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