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Injectable administration is hypothesized to provide systemic distribution, but human pharmacokinetic data for this route does not exist
Plos Pathog
Its important for patients to understand that GLP-1 medications are not a skinny shot, but a tool designed to support metabolic health through long-term weight management
( g ) Degree of mitochondrial outer membrane permeabilization (% MOMP) in HCT116 cells 5FU when treated with compounds as indicated
doi: 10.1111/cei.12882
However, we also know weight loss is extremely helpful in HS, There has to be a balance and an awareness of the potential of improvement of HS due to weight loss and yet increase in acne secondary to the medication and hormonal changes. This does not mean that taking patients off GLP-1 receptor agonists is the answer, but it does mean that dermatologists must be aware of this growing drug class that may bring patients, particularly adult women, into their offices for acne vulgaris
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