This non-invasive method is preferred by those who are uncomfortable with injections
doi: 10.1016/j.metabol.2019.154013 24 WangJLiuHYueGDengYCaiWXuJ
Although the reason why this is the case is poorly understood - patients with prostate cancer may have lower free PSA levels than those with a benign prostate condition
thus, resistant peptic ulcers equal to resistant chronic skin ulcers, both unable to heal (Skorjanec et al., 2009)
doi: 10.1038/nature08821 9 GengJNiQSunWLiLFengX
Dose selection by research model Representative doses by endpoint: Cardiac post-MI (mouse): 150 g/kg IP, often single or repeated dosing in acute protocols Cardiac post-MI (rat): higher absolute doses, scaled by species weight Skeletal muscle injury (rat): 2-10 mg per animal, IM or SC, weekly for 2-6 weeks Dermal wound healing: topical or systemic dosing depending on design Corneal wound healing: topical administration in eye drops (specialised formulation) CNS / stroke models: typically IP or SC systemic administration 9
