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[3] GHRP-6 and the CD36 receptors It is posited that GHRP-6, a growth hormone-releasing peptide, may potentially interact with receptor sites other than those specifically related to ghrelin, known as GHS-Rs

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Why cold storage matters: peptide bonds in solution are susceptible to hydrolysis, and aggregation (where peptide chains clump together, losing receptor-binding activity) accelerates at room temperature

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Taken together, these studies suggest that the endocrine action of IGF-1 plays a lesser role in skeletal growth, and is mostly confined to periosteal growth