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It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions

7), with the formation of a lactam bridge through the side chain of glutamic acid or aspartic acid with lysine 169 , the formation of disulfide bonds by replacing residues with cysteine or homocysteine 170 , and biselectrophilic linkers 171,172