Concurrently, Ca 2+ overload activates calcium-dependent proteases (e.g., calpain) and phospholipases (e.g., Phospholipase A2 (PLA2)), which degrade cytoskeletal proteins (e.g., actin, tubulin) and membrane phospholipids, ultimately resulting in plasma membrane rupture [175]
Enhanced GH secretion during sleep supports multiple recovery processes including tissue repair, immune function optimization, and metabolic regulation
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