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179 Curcumin may also reduce serum cholesterol by increasing the production of the LDL receptor, 180,181 but despite successes in animal models, human data on the anti-hypercholesterolemic effects of curcumin is conflicting

(123) found that the microbial metabolite p-cresol can inhibit gut hormone expression and regulate small intestinal transit, suggesting its important role in intestinal metabolic regulation

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The common causes of knee injury include: Fracture of the femur (thighbone) or tibia and fibula (leg bones) Torn ligament: either anterior or posterior cruciate ligament (ACL or PCL) Rupture of blood vessels following a trauma that leads to the accumulation of extra fluid or blood in the joint Dislocation of the kneecap (patella) Torn quadriceps or hamstring muscles Patellar tendon tear Types of Ligament Injuries The most common types of ligament injuries include: ACL tear An ACL injury is a sports-related injury that occurs when the knee is forcefully twisted or hyperextended