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Preclinical studies have demonstrated that NCoR1 depletion, followed by treatment with rapamycin, anti-mycin-A, or metformin restored TFEB activity and LC3 levels, leading to improved clearance of M.tb [28]

Likewise, fortifying salt and milk products with iodine ensures an adequate amount of dietary iodine (172, 173)

Drinking alcohol can affect endocrine function

Chem Res Toxicol 20:14821487

In addition to its effects on enzyme activity, insulin exerts effects on the transcription of numerous genes, effects that are primarily mediated by regulating the activity of the transcriptional co-activator, PGC-1