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Evidence for a direct link between glutathione biosynthesis and stress defense gene expression in Arabidopsis

Particularly, the development of patient-friendly modalities such as microneedle-assisted delivery systems and barrier-restorative topical nanoplatforms represents the most immediate and promising translational opportunity to bridge the gap between bench research and clinical practice

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its core mechanism involves iron ion-catalyzed lipid peroxidation

Spermidine can reduce the expression of TFR1 and ALOX15, and upregulate Nrf2 and SLC7A11 expression