Ipamorelin is a growth hormonereleasing peptide (GHRP) that mimics ghrelin, a hormone involved in GH release
Bo et al., 2019) suggesting a regulatory relationship (Mahana et al., 2016
This process slows down how food moves in your stomach
The programme spans multiple trials targeting distinct endpoints: On 21 May 2026 Eli Lilly reported topline results from TRIUMPH-1, the pivotal Phase 3 obesity trial and the programme's first Phase 3 efficacy readout: in 2,339 adults, mean weight loss at the 80-week primary endpoint reached 19.0% (4mg), 25.9% (9mg), and 28.3% (12mg) versus 2.2% for placebo (Eli Lilly investor release
Cell Stress and Chaperones 25, 909917
Mosconi L, Sorbi S, de Leon MJ, Li Y, Nacmias B, Myoung PS, et al