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622 Clinical imaging showed increased iron signaling in the basal ganglia and decreased iron in the white matter and cortex in HD patients

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Wei W, Wang H, Wu Y, Ding K, Li T, Cong Z, et al

(108) found that long-term fasting-mimicking diet (FMD) cycles reduced hippocampal A load and tau hyperphosphorylation in E4FAD and 3xTg AD mouse models, enhanced neurogenesis, reduced the number of microglia, and decreased the expression of neuroinflammatory genes, including the superoxide-producing NADPH oxidase (Nox2)

He avoided rebound weight gain, improved his A1C from 6.4% to 5.5%, and saw a 30% drop in triglycerides

We denote this end of the trajectory as the most like. Despite higher expression of GCG than INS , the -2 subcluster was located closer to the -like end of the trajectory