High-dose supplementation, particularly hydroxocobalamin injections, has been associated with acne-like eruptions and rosacea flare-ups in susceptible individuals
The latter seems to be the most likely possibility since even custom-synthesized peptides that were substrate analogs (of GSH) failed to be effective as ChaC1 inhibitors
Biomedicine & Pharmacotherapy , 57(34), 145155
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People may microdose GLP-1 medications for many reasons, including: They have hit their target weight goal They have concerns about the cost of the medications They are sensitive to the side effects of the medications They want to just suppress their appetite They are worried about the supply of the medications Microdosing GLP-1 medications can come with real risks, including: Inaccurate doses Reduced effectiveness Unpredictable outcomes Possibility of regaining weight No data on the long-term effects of microdosing Minimal oversight Large clinical trials have confirmed that the standard GLP-1 doses work well when helping people lose weight and manage Type 2 diabetes
Neoplasia 29 , 100800 (2022)
