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Beyond central nervous system disorders, cognitive assessments will play vital roles in various therapeutic areas: Epilepsy studies will focus on cognitive impacts of seizures and medications Migraine research will examine cognitive function during and after episodes Phase I trials will incorporate cognitive testing for neurological safety monitoring Heart failure studies will track cognitive function as a key comorbidity measure In these ways, the proliferation in adoption of cognitive testing will support more accurate and patient-centered clinical data

Always follow your doctor's guidance on how to do this safely and effectively

M., Bonelli, M., Gadina, M

4 About the Compound 5-Amino-1MQ is a quinolinium salt a small, water-soluble, membrane-permeable molecule (not a peptide)

Cagrilintide Storage & Handling Cagrilintide Storage Reference State Lyophilized (powder) Storage -4F (-20C) freezer Duration Up to 24 months State Lyophilized (short-term) Storage 35.6-46.4F (2-8C) refrigerator Duration Acceptable for shipping or short storage State Reconstituted (liquid) Storage 35.6-46.4F (2-8C) refrigerator Duration 28-30 days

Proc Natl Acad Sci USA 1996