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GLP-1s and Metabolic Health Metabolic dysfunction, which includes conditions like obesity, type 2 diabetes, and metabolic syndrome, is often at the core of many chronic diseases

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doi: 10.1080/14656566.2020.1748599 168 KadouhHChedidVHalawiHBurtonDDClarkMMKhemaniDet al

Higher HbA1c has also been consistently associated with cardiovascular disease risk, worse cognitive aging, increased liver fat, early kidney impairment, higher inflammation, reduced fertility, and higher mortality risk

256 Another study revealed elevated levels of p53 and proapoptotic proteins, including caspase-3, caspase-8, Bax, and Fas, in spinal motor neurons from individuals with ALS, whereas p53 levels were not altered in neurons of the motor cortex