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Research demonstrates BPC-157 works primarily through activation of the VEGFR2 (vascular endothelial growth factor receptor 2) and modulation of nitric oxide signaling via the Akt-eNOS pathway

Vascular and angiogenic endpoints include: VEGF expression CD34 markers factor VIII markers vascular density endothelial response eNOS signalling NO pathway markers blood flow related tissue response This pathway helps explain why BPC-157 appears in so many different tissue models

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