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Animal studies using euglycemic clamp techniques, the gold standard for insulin sensitivity assessment, confirmed that chronic AOD-9604 treatment produced no adverse effects on insulin sensitivity

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13 In addition to being recommended in patients with ASCVD, GLP-1 receptor agonists are recommended for consideration as an add-on to metformin in patients without established ASCVD in whom there is a compelling need to minimize hypoglycemia, minimize weight gain, or promote weight loss

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When you follow your scheduled injection plan, each new dose builds on the residual medication already circulating, maintaining steady therapeutic levels that support consistent appetite control and metabolic benefits