Translational Gap: None for the mechanism itself
Milewska, E
The application of anti-cholinergic agents (scopolamine, atropine, 10 mg/kg b.w., i.p.) led to a significant cognitive deficit in the rats, a finding successfully reproduced assessing the animals behavior in water T-maze for a prolonged period
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GLP-1's Next Frontier Since GLP-1 drugs are believed to act on brain regions involved in reward and motivation, they may also have potential in the treatment of substance use disorders, including opioid, alcohol, and nicotine addiction, according to researchers