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The Food Standards Agency recommends healthy adults limit caffeine to 400mg daily (approximately four cups of brewed coffee), which remains applicable when taking Wegovy

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Tirzepatide's extended half-life (approximately 5 days) and dual GIP/GLP-1 receptor activation create a slower absorption profile compared to shorter-acting GLP-1-only therapies

To minimise any potential effect, patients should continue taking levothyroxine as directedtypically 3060 minutes before breakfast on an empty stomachand maintain consistent timing