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And the entire step-wise series of reactions that oxidize fatty acids and glucose can be called either the Krebs cycle (after its discoverer, Hans Krebs) or the tricarboxylic acid cycle (TCA) cycle

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Lee PDK, Lustig RH, Feldman HA, Glaser Obesity Study Group: Insulin-Like Growth Factor-Binding Protein-1 (IGFBP-1) predicts insulin sensitivity and area-under-the-curve insulin (AUC)

Thus, IOA-289 represents the most advanced ATX-targeting agent in clinical oncology, and its development provides a strong rationale for evaluating ATX inhibition as a novel therapeutic strategy for CRPC

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