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Start your intake How Topiramate and GLP-1 Medications Work Differently Topiramate (Topamax) reduces appetite through multiple pathways: it enhances GABA signaling in the brain, blocks carbonic anhydrase, and modulates sodium channels

However, because it's fortified with several vitamins and minerals, you might not want to pair it with a multivitamin

Vitamin D, in particular, deserves attention because deficiency is common in people pursuing weight loss and can affect bone health, mood, and immune function

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