glp-1 agonists pill New Foundayo (Orforglipron) Gets FDA Approval for Obesity GLP-1 Pills for Weight Loss:

Nixtamal and corn masa flour can be fortified with vitamins and minerals 435,436

Endocr Rev 44(4):737751 Vreugdenhil G et al (1998) Molecular mimicry in diabetes mellitus: the homologous domain in coxsackie B virus protein 2 C and islet autoantigen GAD65 is highly conserved in the coxsackie B-like enteroviruses and binds to the diabetes associated HLA-DR3 molecule

Research has also looked at improve skin structure, skin density, and anti ageing mechanisms at a cellular level

This doesnt mean that taking B12 is always without side effects, however

The body can also convert tryptophanan amino acidto nicotinamide

Nanchal R, Subramanian R, Karvellas CJ, Hollenberg SM, Peppard WJ, Singbartl K et al (2020) Guidelines for the management of adult acute and acute-on-chronic liver failure in the ICU: cardiovascular, endocrine, hematologic, pulmonary, and renal considerations