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The polyketide chain undergoes cyclization and dehydration to form Noranthrone, an early intermediate in the pathway

Annals Of Internal Medicine 1993, 119: 1084-90

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While GHK-Cu treatment alone did not cause any visible histological changes or toxicity, pretreatment with GHK-Cu markedly attenuated these pathological alterations, resulting in a significantly reduced lung injury score compared to the LPS-only group

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