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501 Activation of Nrf2 prevents ferroptosis by upregulating ferritin, SLC7A11 and GPX4

Catalases may have another role: the generation of ROS, possibly hydroperoxides, upon UVB irradiation

2010 Feb;27(2):83-90

But its also for cytoprotection

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Correlation of brain-derived neurotrophic factor with severity of depression and treatment response