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Also, the significance of this peptide's therapeutic benefit against amplified and advanced paracetamol toxicity remains to be further postulated, particularly considering the extensive investigation of gastrointestinal peptides in gastrointestinal and liver physiology (38), physiological mediators in NSAIDs-induced impairment of gastric mucosal defense and adaptation (39), and brain-gut peptide regulation (40)

doi: 10.1016/j.phrs.2024.107445 575 ZhouQDaiWBaoYChenJHanXLiuCet al

doi: 10.1016/S0021-9258(18)84368-X

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Panax notoginseng saponins mitigate cisplatin induced nephrotoxicity by inducing mitophagy via HIF-1