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This work was supported by the Yuhan Innovation Program and the National Research Foundation of Korea (NRF) [2021R1A2C1004669 and RS-2024-00411137], funded by the Korean government (MSIT) and by the KBSI under the R&D program [Project No

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Figure 4 It is thought that many chronic illnesses, including ME/CFS, originate with reactivation of latent or dormant viruses that are present in the body, caused by a change in physiological conditions (127)

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Dopamine supplementation would be evident, but this hydrophilic neurotransmitter does not cross the BBB and cannot enter the CNS due to brain endothelial tight junctions, active brain endothelial metabolism and lack of transporters [5]