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Inclusion Criteria Exclusion Criteria Timeline for a Trial Participant Screening Participants are screened for eligibility to participate in the trial Treatment Participants receive intravenous bimagrumab and subcutaneous semaglutide according to the dose escalation schedule Follow-up Participants are monitored for safety and effectiveness after treatment Extension Participants may continue to receive bimagrumab during the extension period What Are the Treatments Tested in This Trial