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For the tens of millions of men now taking glucagon-like peptide-1 receptor agonist medications Ozempic, Wegovy, Victoza, Saxenda for obesity or type 2 diabetes, a question with direct reproductive consequences has lingered without a clinical answer: what are these blockbuster drugs actually doing to male hormones and sperm

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Site directed and saturation mutagenesis were performed using the Quikchange II kit (Agilent Technologies) or by overlapping PCR

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In February 2024, a federal panel combined 55 Ozempic and related GLP-1 lawsuits into a separate multidistrict litigation (MDL-3094) in the Eastern District of Pennsylvania

It has been banned by the World Anti-Doping Agency since 2022, as well as by the NFL, UFC, and other sports organizations