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Avoid freezing the mixed solution and do not subject it to repeated freezethaw cycles

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Table 17: Exploratory Efficacy Analyses by Histologic Subgroup in Study JMEI The efficacy of pemetrexed was evaluated in Study JMCH (NCT00005636), a multicenter, randomized (1:1), single-blind study conducted in patients with MPM who had received no prior chemotherapy

[2] Nevertheless, the principle of taking supplements only when clinically indicated remains important