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Front Pharmacol (2020) 11:356

39 An increase in hypothalamo-pituitary adrenal activity is seen as having adaptive endocrine effects and behavioral consequences via its influence on memory and arousal

Pregnancy prevention is critically important

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Main causes: Ultra-processed food (low in fiber, high in simple sugars) Unbalanced gut microbiota (dysbiosis) Insulin resistance (prediabetes) Lack of sleep (reduces production by 30%) Chronic stress (cortisol inhibits GLP-1) Sedentary lifestyle Good news: Unlike your genetics, your GLP-1 production is completely modifiable by your lifestyle choices