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282 Therapeutic modulation of the autophagy-mitophagy axis in cancer Autophagy inhibition in cancer therapy Autophagy inhibition has been extensively explored in oncology

It has been previously shown that cyclosporin A could protect from tumor necrosis factor-alpha (TNF-alpha)-induced acute hepatic injury when administered as multiple-interval injections but not as pre- or concomitant single-injections 56,58