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You should wait at least 30 minutes after taking Rybelsus before taking paracetamol or any other oral medication

[iii] Holst JJ

The seventh embodiment of the present invention provides a process for the preparation of compound of formula-3a (Semaglutide side chain), comprising: a) preparation of compound of formula- 13 as per the process described above, b) reacting compound of formula- 13 with compound of formula- 14a in a solvent optionally in presence of a coupling agent and/or a base to provide compound of formula- 15a Formula- 14a Formula- 15a c) treating compound of formula- 15a with a deprotecting agent optionally in presence of a solvent to provide compound of formula-3 a