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Importantly, it also upregulates glutamatecysteine ligase modifier subunit ( GCLM ) ( GCLM limits GSH synthesis and leads to functional inactivation of GPX4 (

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Deficiency of mitochondrial glycerol 3-phosphate dehydrogenase contributes to hepatic steatosis

[10] [12] It may reduce the efficacy of certain anticoagulants, such as warfarin, by affecting hepatic metabolism or interfering with laboratory monitoring of coagulation parameters

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