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Small Sample Sizes Human evidence is limited and often lacks rigorous study design
CREB activation is linked to neural plasticity and the therapeutic effects of antidepressants, whereas NF-B activation is associated with inflammatory responses and may exacerbate depressive symptoms [367, 368]
10.1016/j.reprotox.2023.108368 47 MoradiM.HashemianM
Another commenter stated that retaining the HEBA but eliminating the health equity adjustment undermines CMS' stated policy goal of supporting ACOs that serve vulnerable population and incentivizing long-term participation of these ACOs
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