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Klotho suppresses indoxyl sulfate-mediated apoptosis in human kidney proximal tubular (HK-2) cells through modulating the AKT/Nrf2 mechanism

Characterization of the influence of vildagliptin on model-assessed -cell function in patients with type 2 diabetes and mild hyperglycemia

The increased Bax/Bcl-2 ratio promotes mitochondrial outer membrane permeabilization and cytochrome c release, leading to the activation of caspase-9 and downstream executioner caspase-3 (78)

Ding K, Liu C, Li L, Yang M, Jiang N, Luo S, et al

Manson points out

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