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The plasmids and SiRNAs were transiently transfected using the jetPRIME Transfection Reagent (101000046, Polyplus) following the manufacturers protocol

445 Furthermore, in IMIDs, activated platelets influence their phenotype through interactions with innate and adaptive immune cells, promoting inflammatory and autoimmune responses with higher circulating levels of their aggregates

GTPase signaling Guanosine triphosphatases (GTPases) are a group of enzymes that hydrolyze guanosine triphosphate (GTP) to guanosine diphosphate (GDP) and inorganic phosphate

Many patients struggle with persistent hunger, slow progress, or weight regain despite making healthy lifestyle changes