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Since gain-of-function mutations in NLRP3 were demonstrated to cause a rare autoinflammatory disease termed cryopyrin-associated periodic syndrome, NLRP3 has emerged as key mediator of inflammation in mouse models for many common diseases, including atherosclerosis, Alzheimers disease and gout

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El-Ansary A, Bjrklund G, Tinkov AA, Skalny AV, Dera HA (2017) Relationship between selenium, lead, and mercury in red blood cells of saudi autistic children