The kill switch of engineered live bacteria is difficult to maintain stability due to the application of strong selective pressure, and there may be a risk of escape mutations in the bacterial community in complex environments
Information about data access request proposals can be found at Change history 28 May 2024 In the version of the article initially published, in Fig
Jastreboff et al., NEJM 2023)
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Proc Natl Acad Sci USA 93 : 1325013255
Review literature discussing these models frequently highlights the interaction between BPC-157 and nitric oxiderelated signaling systems involved in epithelial-endothelial communication and mucosal barrier maintenance [2]